Alzheimer’s Research Opportunities

The knowledge that we gain through clinical research helps improve the ways we can prevent, diagnose, and treat Alzheimer’s and dementias– but researchers can’t do it alone. They need volunteers in order to improve the lives of those who have been affected by Alzheimer’s or other dementias. Click here to learn more about clinical trials and decide if it’s right for you and your family.


There are a number of research opportunities in the Toronto area currently searching for participants:


Introducing the Alzheimer Society Research Portal!

This research portal connects researchers with Canadians looking to participate in studies. This initiative will help to advance Canadian studies on Alzheimer’s disease and other dementias.

To get involved, please refer to the contact information on the current study listed: Talk2Me: an online study of language changes associated with dementia.

Pharmaceutical and clinical trials are not included in the Alzheimer Society Research Portal. However, you can find these studies at To learn more about participating in research, please visit: Participating in research.

To submit a study asking for participants, please complete and submit the online application form.

Each study listing includes a description of the study and its location; start and end dates; eligibility criteria; and contact information for those interested in participating in the study. To be eligible, studies must be supported by the Alzheimer Society Research Program (ASRP) or other recognized funding agencies in Canada that have a formal committee review process. Studies related to pharmaceutical or biotechnology companies, marketing research firms or other for-profit enterprises are not eligible for posting on the Research Portal.


The Toronto Memory Program’s Azeliragon for the Treatment of Patients with Mild Alzheimer’s disease

Toronto Memory Program is Canada’s largest and most experienced site for Clinical Trials in Alzheimer’s disease and related conditions such as vascular dementia. The process begins with an educational session. You and your study partner will meet with research staff at the facility. The staff will explain the nature of study participation in detail as well as the specifics of any study of interest. Click on the link above to see if you qualify.


Dementia in Canada: What do you think? Study

The Canadian Dementia Priority Partnership wants to know where you think we need research related to living with dementia as well as dementia prevention, diagnosis and treatment. The research priorities identified from this study will be shared with researchers and research funding organizations so that they can incorporate them into their research agendas. You can complete the short questionnaire here:


The Rotman Research Institute’s Driving and Dementia Study:

Researchers at Baycrest Health Sciences are conducting a study on Driving and Dementia to learn how to support persons with dementia and their family members and loved ones make decisions about driving and stop driving when the time is right. Their objective is to develop an intervention that helps to balance quality of life of older adults with the safety concerns that come with dementia. Participants must be either the family member or friends of someone with dementia who drives or recently stopped driving, drivers with mild dementia, or people with mild dementia who have recently stopped driving.


This study is looking for volunteers to take part in a research project that has the goal to create an online tool that connects family caregivers to resources they need to support themselves and an individual with dementia. The participants must be 18 years or older, must be able to speak English, and have one year experience of caring for a family member or friend with dementia who lives at home.


Ryerson University’s Faculty of Community Services’ Decreasing Loneliness Study:

You may be eligible for a research study to provide your opinions about interventions that can be used to decrease loneliness for people with dementia. This study is looking for participants 21 years or older who have a friend or a relative living with dementia; or participants aged 65 or older living with mild to moderate dementia. Participation is voluntary and takes about 2 hours. In appreciation of your time and travel, you will receive a $60 cash incentive.


Cogniciti’s Health-e Brain Study:

This study is focused on the cognitive health of caregivers, taking place over a 12-week period from your computer or the comfort of your own home. With the launch of this study, we can now help researcher develop a new “Mobile Mirror for Caregivers”. Too often caregivers are overlooked when it comes to health and care, and it’s time to take action for those who help others. All potential participants will need to register on the website and take a demographics survey, a sleep survey, a caregiver burden survey, and a behavioural survey.


Focused Ultrasound Therapy Study at Sunnybrook

Sunnybrook is looking for volunteers to participate in an ongoing research activity within the Division of Neurosurgery. Health Canada has recently approved the safety and feasibility of MRI-guided focused ultrasounds for patients with Early Onset Alzheimer’s. Participants should be those with Early Onset Alzheimer’s, ideally younger than 75 years of age, who are interested in progressing Focused Ultrasound therapy.

For details, please call: (416)-480-6100 ext. 3773, or email: See for additional info.


“Tele-Mindfulness” Study

Mindfulness is paying attention to the present moment with awareness and without judgement. Through training in mindfulness, individuals have learned how to use their innate resources and internal abilities to manage stress and challenging emotions more effectively which might be of benefit for caregivers. “Tele-mindfulness for family caregivers of dementia patients” is a study to see if mindfulness can be helpful to caregivers when provided at home over the internet on their computer. If you are taking care of someone with dementia, you may be eligible to participate in this study.

For more information please call 416-586-4800, ext. 5882 or email:


Language and Dementia Research Study

This study is seeking volunteers to take part in a study regarding language and dementia. The study looks to investigate how features of language, such as the complexities of sentences, types of words being used, voice characteristics, and the topics discussed, differ between healthy adults and those with Alzheimer’s Disease. Participants must either be over 44 years old, and cognitively healthy, or over 44 years of age, and have been diagnosed with Alzheimer’s (seeking 2 groups of volunteers). During the study, participants may be asked to complete language exercises using computer-based assessments at the Scarborough Centre for Healthy Communities. Participation involves 4 sessions, 1 per week; it will take about 120 minutes in total, spread over 4-5 weeks. Participants will also receive a $20.00 gift card and letter of appreciation signed by the study investigators.

For more information, please call Jaimie Chan at (416)-847-4132, or email:


Insomnia Patients with Mild to Moderate Alzheimer Disease Research Study

The purpose of this clinical research study is to evaluate whether the investigational medication is effective and safe, compared with placebo, in improving insomnia in patients with insomnia and Alzheimer’s disease. The study will need participants aged 50 to 90 years old who have been diagnosed with insomnia and mild to moderate Alzheimer Disease; participants must also have a competent and reliable trial partner willing to administer and complete study procedures and assessments. The overall study is composed of 3 weeks screening period, 4 weeks double-blind treatment period and 14 days post-treatment telephone contact. There will be 6 clinic visits, three of which will be overnight sleep study; recruitment is starting now – until July 31st, 2017. While the study will take place both at the client’s home and at the Research Centre and Sleep Laboratory, participants will be reimbursed for any transportation costs, in addition to reimbursement for the nights spent in the sleep laboratory.

For more information, please contact Urszula Lamoureux at


“Listening while Walking” Study – multitasking challenges in mild cognitive impairment and early Alzheimer’s Disease patients

The Real-World Multitasking Challenges study investigates the impact of age-related changes in sensory and cognitive functioning on safe mobility in older adults. Toronto Rehabilitation Institute is looking for healthy adults aged 60 years and older, and individuals diagnosed with mild cognitive impairment or early-stage Alzheimer’s disease. Participation will involve measures of hearing, vision, balance, and cognition, and the experiment will take place within a state-of-the-art Virtual Reality laboratory. Participation is completely voluntary and is scheduled at your convenience. Participants will also be compensated $10/hour for their time (i.e. $20 for the first session, $25 for the second). Recruitment begins January 1st – October 1st, 2017, and takes place in the Toronto Rehabilitation Institute and the U of T Rehabilitation Sciences Building.

For more information, please contact Sophie Carr at


Developing an imaging biomarker for Alzheimer’s dementia based on vascular dysfunction

The purpose of this study is to determine whether we can use advanced MRI to detect early changes in Alzheimer’s disease and to distinguish these changes from other forms of dementia. This new information would be a major advance in our understanding of the development of Alzheimer’s disease that may lead to earlier treatment and diagnosis. Participants must be 50 years of age or older and fluent English speakers. Compensation will be provided per visit with overall visit time being 1.5 hours.

For more information, please contact Abby Skanda at or by phone at 416 603 5800 ext.6586.


Caring for Alzheimer’s throughout the Disease Study

Are you caring for a person with Alzheimer’s disease? Do you want to help future caregivers? You are invited to participate in a study by Occupational Therapy Students from the University of Toronto called “Caring for Alzheimer’s Throughout the Disease.” We would like to speak with you to learn about your experiences and needs from the moment you noticed symptoms of dementia in the person you are caring for, to how you are managing today and as you look to the future. The purpose of this study is to learn about caregivers’ experiences and support needs and how they change over time. To participate, you must be living in Ontario with the individual with Alzheimer’s Disease who is diagnosed at least one year ago. Recruitment for this study will end April 30th, 2017.

For more information, please contact Samantha D’Souza, MScOT(c) at


The Dementia Sibling Study: Brothers and Sisters Sharing Caregiving Experiences

Are you and your sibling caring for a parent with dementia? Occupational Therapy students from the University of Toronto are conducting a study looking at the experiences and support needs of caregivers. Share your caregiving experiences through an online survey!

This study is specifically recruiting adult daughter and son pairs; the purpose is to explore how caregiving responsibilities are shared between adult daughters and sons in the care of a parent with dementia. Participants must be 18 years or older, must live in Canada, and must also speak English; the study includes a 30 to 45-minute online survey. Recruitment has begun now and will end May 31st, 2017. Participants have the option of entering their name and contact information at the end of the survey to be entered into a draw for a chance to win one of two $25 Chapters gift cards.

For more information, please contact Lily Nguyen at


To stay up-to-date with all the research opportunities available in Toronto, keep checking back here on our blog.

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